Literatur & Links

Publikationen

In der nachfolgenden Auflistung sind nur Studien aufgeführt, die einem Peer-Review unterzogen wurden und deren Erst- oder Letztautor:in Mitglied des Arbeitskreises Polytrauma ist.

Mortality in Moderate to Severe Traumatic Brain Injury in Elderly Polytrauma Patients at a European Level 1 Trauma Centre: A Retrospective Cohort Study.
Nia A, Leitgeb J, Widhalm HK, Popp D, Schmoelz L, Döring K, Wall D, Aldrian S. J Clin Med. 2025 May 29;14(11):3843. doi: 10.3390/jcm14113843. PMID: 40507605.

The Characteristics of Severely Injured Trauma Patients Admitted to a Level I Trauma Center with Pre-Injury Use of Oral Anticoagulation (OAC) or Antiplatelet Therapy (APT).
Weihs V, Antoni A, Frenzel S, Aldrian S, Hajdu S, Negrin LL. J Clin Med. 2025 May 21;14(10):3614. doi: 10.3390/jcm14103614. PMID: 40429609.

MIP-3-Alpha and MIP-3-Beta as Early Predictors of Pneumonia in Polytraumatized Patients.
Wollner G, Hruska F, Ettel P, Weichhart T, Koenig FRM, Negrin LL. Lung. 2025 Mar 13;203(1):44. doi: 10.1007/s00408-025-00799-2. PMID: 40074940.

Sex-Based Differences in Polytraumatized Patients between 1995 and 2020: Experiences from a Level I Trauma Center.
Weihs V, Babeluk R, Negrin LL, Aldrian S, Hajdu S. J Clin Med. 2024 Oct 8;13(19):5998. doi: 10.3390/jcm13195998. PMID: 39408058.

Heterotopic Ossifications Following Intramedullary Stabilization of Femoral Fractures in Polytraumatized Patients.
Wollner G, Hruska F, Koenig FRM, Haider T, Negrin LL. J Clin Med. 2024 Sep 19;13(18):5557. doi: 10.3390/jcm13185557. PMID: 39337042.

Differences in Eotaxin Serum Levels between Polytraumatized Patients with and without Concomitant Traumatic Brain Injury-A Matched Pair Analysis.
Negrin LL, Ristl R, Wollner G, Hajdu S. J Clin Med. 2024 Jul 19;13(14):4218. doi: 10.3390/jcm13144218. PMID: 39064258.

Time trajectories and within-subject correlations of matrix metalloproteinases 3, 8, 9, 10, 12, and 13 serum levels and their ability to predict mortality in polytraumatized patients: a pilot study.
Negrin LL, Carlin GL, Ristl R, Hajdu S. Eur J Med Res. 2024 Apr 10;29(1):225. doi: 10.1186/s40001-024-01775-x. PMID: 38594750.

Serum levels of matrix metalloproteinases 1, 2, and 7, and their tissue inhibitors 1, 2, 3, and 4 in polytraumatized patients: Time trajectories, correlations, and their ability to predict mortality.
Negrin LL, Carlin GL, Ristl R, Hajdu S. PLoS One. 2024 Mar 8;19(3):e0300258. doi: 10.1371/journal.pone.0300258. eCollection 2024. PMID: 3845745.8

Serum Angiopoietin-2 level increase differs between polytraumatized patients with and without central nervous system injuries.
Negrin LL, Hajdu S. Sci Rep. 2023 Nov 7;13(1):19338. doi: 10.1038/s41598-023-45688-x. PMID: 37935720. 

Musculus psoas major morphology – a novel predictor of mortality in elderly polytraumatized patients.
Wollner G, Weihs V, Frenzel S, Aldrian S, Negrin LL. BMC Emerg Med. 2023 Feb 7;23(1):13. doi: 10.1186/s12873-023-00783-0. PMID: 36750772 18.

25-Year experience with adult polytraumatized patients in a European level 1 trauma center: polytrauma between 1995 and 2019. What has changed? A retrospective cohort study.
Weihs V, Frenzel S, Dedeyan M, Hruska F, Staats K, Hajdu S, Negrin LL, Aldrian S. Arch Orthop Trauma Surg. 2023 May;143(5):2409-2415. doi: 10.1007/s00402-022-04433-1. Epub 2022 Apr 12. PMID: 35412071.

Age and traumatic brain injury as prognostic factors for late-phase mortality in patients defined as polytrauma according to the New Berlin Definition: experiences from a level I trauma center.
Weihs V, Heel V, Dedeyan M, Lang NW, Frenzel S, Hajdu S, Heinz T. Arch Orthop Trauma Surg. 2021 Oct;141(10):1677-1681. doi: 10.1007/s00402-020-03626-w. Epub 2020 Oct 17. PMID: 33070209.

Impact of Polytrauma and Acute Respiratory Distress Syndrome on Markers of Fibrinolysis: A Prospective Pilot Study.
Negrin LL, Dedeyan M, Plesser S, Hajdu S. Front Med (Lausanne). 2020 Jun 2;7:194. doi: 10.3389/fmed.2020.00194. eCollection 2020. PMID: 32582720.

IL-33 and its increased serum levels as an alarmin for imminent pulmonary complications in polytraumatized patients.
Halát G, Haider T, Dedeyan M, Heinz T, Hajdu S, Negrin LL. World J Emerg Surg. 2019 Jul 19;14:36. doi: 10.1186/s13017-019-0256-z. eCollection 2019. PMID: 31360218.

Systemic release of heat-shock protein 27 and 70 following severe trauma.
Haider T, Simader E, Glück O, Ankersmit HJ, Heinz T, Hajdu S, Negrin LL. Sci Rep. 2019 Jul 3;9(1):9595. doi: 10.1038/s41598-019-46034-w. PMID: 31270381.

The Importance of Sex Differences on Outcome after Major Trauma: Clinical Outcome in Women Versus Men.
Joestl J, Lang NW, Kleiner A, Platzer P, Aldrian S. J Clin Med. 2019 Aug 20;8(8):1263. doi: 10.3390/jcm8081263. PMID: 31434292.

The impact of polytrauma on sRAGE levels: evidence and statistical analysis of temporal variations.
Negrin LL, Ristl R, Halat G, Heinz T, Hajdu S. World J Emerg Surg. 2019 Mar 18;14:13. doi: 10.1186/s13017-019-0233-6. eCollection 2019. PMID: 30923559.

Diagnostic Utility of Serum Neutrophil Gelatinase-Associated Lipocalin in Polytraumatized Patients Suffering Acute Kidney Injury: A Prospective Study.
Negrin LL, Hahn R, Heinz T, Hajdu S. Biomed Res Int. 2018 Nov 6;2018:2687584. doi: 10.1155/2018/2687584. eCollection 2018. PMID: 30533430.  

A Novel Approach to Identify Polytraumatized Patients in Extremis.
Negrin LL, Antoni A, Hajdu S, Heinz T. Biomed Res Int. 2018 Apr 17;2018:7320158. doi: 10.1155/2018/7320158. eCollection 2018. PMID: 29850559.

Increased serum concentrations of soluble ST2 are associated with pulmonary complications and mortality in polytraumatized patients.
Haider T, Simader E, Hacker P, Ankersmit HJ, Heinz T, Hajdu S, Negrin LL. Clin Chem Lab Med. 2018 Apr 25;56(5):810-817. doi: 10.1515/cclm-2017-0762. PMID: 29341938.

Does the applied polytrauma definition notably influence outcome and patient population? – a retrospective analysis.
Frenzel S, Krenn P, Heinz T, Negrin LL. Scand J Trauma Resusc Emerg Med. 2017 Aug 31;25(1):87. doi: 10.1186/s13049-017-0400-2. PMID: 28859678. 

Thoracic trauma and acute respiratory distress syndrome in polytraumatized patients: a retrospective analysis.
Haider T, Halat G, Heinz T, Hajdu S, Negrin LL. Minerva Anestesiol. 2017 Oct;83(10):1026-1033. doi: 10.23736/S0375-9393.17.11728-1. Epub 2017 Apr 11. PMID: 28402091.

Club cell protein 16 and cytokeratin fragment 21-1 as early predictors of pulmonary complications in polytraumatized patients with severe chest trauma.
Negrin LL, Halat G, Kettner S, Gregori M, Ristl R, Hajdu S, Heinz T. PLoS One. 2017 Apr 5;12(4):e0175303. doi: 10.1371/journal.pone.0175303. eCollection 2017. PMID: 28380043.

Leptin Protects Against Mortality and Organ Dysfunction in A Two-Hit Trauma/Sepsis Model and is IL-6-Dependent.
Negrin LL, Jahn A, van Griensven M. Shock. 2017 Jul;48(1):130-137. doi: 10.1097/SHK.0000000000000837. PMID: 28114167.

The clinical benefit of a follow-up thoracic computed tomography scan regarding parenchymal lung injury and acute respiratory distress syndrome in polytraumatized patients.
Negrin LL, Prosch H, Kettner S, Halat G, Heinz T, Hajdu S. J Crit Care. 2017 Feb;37:211-218. doi: 10.1016/j.jcrc.2016.10.003. Epub 2016 Oct 12. PMID: 27969573.

[Polytrauma and concomitant traumatic brain injury: The role of the trauma surgeon].
Antoni A, Heinz T, Leitgeb J. Unfallchirurg. 2017 Sep;120(9):722-727. doi: 10.1007/s00113-017-0354-x. PMID: 28612105 Review.

Soluble Receptor for Advanced Glycation End Products Quantifies Lung Injury in Polytraumatized Patients.
Negrin LL, Halat G, Prosch H, Hüpfl M, Hajdu S, Heinz T. Ann Thorac Surg. 2017 May;103(5):1587-1593. doi: 10.1016/j.athoracsur.2016.09.021. Epub 2016 Nov 16. PMID: 27865475.

Links

PubMed
https://pubmed.ncbi.nlm.nih.gov/

Jahresbericht 2025 des TraumaRegister DGU®
https://www.auc-online.de/fileadmin/AUC/Dokumente/Register/TraumaRegister_DGU/TR-DGU-Jahresbericht_2025.pdf